modafinil will lessen the level or impact of mavacamten by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.In animal scientific tests, the median lethal dose (LD50) of modafinil may differ amongst species and depends on the route of administration. In mice and rats, the LD50 is somewhere around 1250 mg/kg if administered by
Mysterious; not sympathomimetic; may possibly boost dopamine stages while in the brain by binding to the dopamine transporter and inhibiting dopamine reuptakeNo withdrawal symptoms have been noticed in individuals with modafinil therapy cessation for the duration of 14 times of observation, but in individuals with narcolepsy, sleepiness returned.Un
The results of modafinil on reaction latency together with accuracy may also be specially telling. Modafinil confirmed greater reaction latency occasionally, especially in TOL spatial organizing process (Turner et al 2003, 2004a, b; Randall et al 2005), and modafinil commonly brought about diminished reaction latency in exams of awareness and impul